New Research Confirms Exercise Significantly Improves Outcomes After Cancer Treatment
NEW RESEARCH CONFIRMS: EXERCISE SIGNIFICANTLY IMPROVES OUTCOMES AFTER COLON CANCER TREATMENT
A groundbreaking international study published in the New England Journal of Medicine shows that structured exercise programs can dramatically
improve outcomes for colon cancer survivors. Known as the CHALLENGE trial, this eight-year study followed nearly 1,000 patients who had completed surgery and chemotherapy for stage II or III colon cancer.
The findings are powerful:
- A 28% lower risk of cancer recurrence
- A 37% reduction in the risk of death over eight years
- An overall survival rate of 90.3% in the exercise group compared to 83% in the control group
These results highlight the critical role physical activity plays in long-term recovery and survivorship.
A Closer Look: The CHALLENGE Trial
Participants were randomized into two groups: one received printed health education materials, while the other followed a structured three-year exercise program. That program included:
- Year 1: Twice-weekly sessions with a personal trainer
- Years 2 & 3: Monthly check-ins to support independent exercise
The goal was to achieve at least 10 MET (metabolic equivalent of task)-hours of activity per week which is roughly equal to:
- 3–4 brisk walks (45–60 minutes each)
- Or 3–4 short jogs (25 minutes each)
Activities ranged from walking and swimming to circuit training and biking.
Why Exercise Works
Regular physical activity may help reduce cancer recurrence and improve overall health by:
- Lowering inflammation
- Enhancing immune function
- Improving insulin sensitivity
- Reducing anxiety and depression
Additionally, exercise can alleviate common post-treatment symptoms such as fatigue, pain, and nausea.
Getting Started: Tips for Survivors
For those recovering from colon cancer, taking the first step toward an active lifestyle doesn’t have to be overwhelming. Experts recommend:
- Talk to Your Doctor Ensure it’s safe to begin a program tailored to your needs
- Start Small Begin with manageable activities and build up gradually
- Stay Supported Partner with a certified trainer or group class
- Track Progress Use a journal or app to monitor improvements
A Powerful Tool in Recovery
“This study reinforces what many of us have observed: staying active after treatment isn’t just good for general health, it can truly change the course of survivorship,” said Dr. Joel Michalski, Medical Oncologist at Nebraska Cancer Specialists. “We encourage patients to view exercise not as optional, but as an integral part of their recovery plan.”
For more information on fitness classes offered at NCS, visit NebraskaCancer.com/movement.
