NCS is the 1st in the Region to offer DigniCap® Scalp Cooling System
Nebraska Cancer Specialists has invested in DigniCap®, a proven approach to reduce chemotherapy-induced hair loss, helping patients maintain privacy, self-esteem and control during a critical period of treatment. The DigniCap® Scalp Cooling System minimizes hair loss from certain chemotherapy treatments for men and women with solid tumor cancers such as those associated with breast, prostate, ovarian, uterine, and other tissues.


Hair loss can be one of the most devastating side effects of chemotherapy and can negatively affect self-image, confidence and overall well-being during treatment.
By using DigniCap to save your hair, you can maintain privacy, identity and a sense of control during treatment.

Reduced temperature to your scalp causes the hair follicles to narrow and cell activity in the area to slow down. This results in decreased blood flow to the scalp so that less chemotherapy reaches the hair follicles.
The cap will go on for a “pre-cooling” period, which prepares your scalp for chemotherapy. It stays on after your infusion for a “post-cooling” period. Because chemotherapy drug levels peak in your system immediately after you complete an infusion, continued constriction of blood flow to your scalp for a few hours after treatment is the best way to protect your hair follicles. The length of the post-cooling period depends on the type of chemotherapy you’re getting and may include the time you’re receiving medications that don’t cause hair loss.
Scalp cooling must be used at every chemotherapy session to be effective. The caps will be fitted prior to treatment and connected to the DigniCap device.
Wash your hair before going to your appointment, preferably on the morning of each scheduled chemo session. You should arrive with damp, clean hair.
Bring the entire kit – cooling wrap, thermal cap, chin strap, headband, spray bottle and wet brush – to the infusion center with you. Since we don’t have spares, patients who arrive without their kit will have to pay for a new one.
Scalp cooling can cause discomfort, including headaches or brain freeze (the pain commonly associated with eating or drinking something cold). Ask your oncologist and the infusion center staff whether you may take a low-dose pain reliever, such as ibuprofen (Advil) or acetaminophen (Tylenol), before you start the cooling process.
An infusion center staff member will seat you at a DigniCap machine and help you with preparations. Staff will spray your hair (having it wet supports the cooling process) and help you place the cap on your head. You’ll have 20 to 30 minutes of scalp cooling prior to the start of your chemo.
Once you start the cooling process, you can’t be disconnected from the machine for the first 30 minutes, so we recommend using the restroom before starting. After the first 30 minutes, you may take restroom breaks of under six minutes. Let a staff member know if you need a restroom break. Your caregiver can accompany you to the bathroom and inform staff when you’re ready to be reconnected.
Be prepared to get cold! We have warm blankets and towels you can use. Electric warming devices, such as electric blankets, are not allowed due to fire code restrictions.
After your infusion is complete, you’ll remain attached to the machine for a post-treatment cooling period. The length of this period depends on your chemotherapy regimen – anywhere from 2 to 3 hours.

In 2015, DigniCap was the first scalp cooling device to receive FDA clearance after completing a rigorous clinical trial in which 66% of patients kept the majority of their hair.
Scalp cooling feels cold, but most people tolerate DigniCap very well. Your doctor may provide a pain reliever if you develop a headache. A warm drink and blanket can also help during treatments.
The goal of scalp cooling is to reduce overall hair loss so that a wig, cap, scarf or other head covering is not needed.
On your first infusion day, you’ll collect your cooling cap kit from the infusion staff.
For every treatment thereafter, you’ll bring the entire kit – cooling wrap, thermal cap, chin strap, headband, spray bottle and wet brush – to the infusion center with you.
DigniCap Scalp Cooling is an FDA-cleared device that can be covered by insurance. Medicare or secondary insurance may help with administration costs, though some out-of-pocket expenses may remain and could be eligible for patient financial assistance programs. A cash price option is also available. In order to confirm benefits, patients are encouraged to reach out to a member of their NCS care team or speak with a patient financial counselor.

DigniCap can be used by patients undergoing chemotherapy for solid tumors such as those associated with breast, prostate, ovarian, uterine and other tissues. For a list of conditions that can make cold caps less effective, visit the DigniCap website.
There are many factors to consider when deciding whether to use DigniCap. Answering these questions may help with your decision:
Even with a cold cap, you will most likely experience some hair shedding or thinning because your hair follicles will be weakened by the chemotherapy. To minimize hair loss during chemotherapy, be as gentle as possible with your hair during your course of treatment and for about two to three months after completing the last cycle of chemotherapy. The following recommendations can help protect your hair:
More hair care tips are available on the DigniCap website.
| Abraxane | Paclitaxel protein bound weekly | 120 minutes |
| AC (Adriamycin/ Cytoxan) | Doxorubicin/cyclophosphamide every 2 or 3 weeks | 180 minutes |
| CMF | Cytoxan/methotrexate/5-fluorouracil (5-FU) | 120 minutes |
| Ellence | Epirubicin every 3 weeks | 120 minutes |
| Ellence/Cytoxan | Epirubicin/cyclophosphamide every 2-3 weeks | 180 minutes |
| Hallaven | Eribulin | 180 minutes |
| Trodelvy | Sacituzumab govitecan-hziy | 180 minutes |
| SGN-LIV1A | SGN-LIV1A every 3 weeks | 180 minutes |
| Taxol | Paclitaxel 80 mg/m2 weekly | 120 minutes |
| Taxol | Paclitaxel 175 mg/m2 every 2 weeks | 120 minutes |
| Taxol/Paraplatin | Paclitaxel/carboplatin every 3 weeks | 120 minutes |
| Taxol/Keytruda* | Paclitaxel weekly/pembrolizumab every 3 weeks | 120 minutes |
| Taxol/Hycamtin* | Paclitaxel every 3 weeks/topotecan every 3 weeks for 3 days | 120 minutes |
| Taxotere/carboplatin | Docetaxel/carboplatin every 3 weeks | 180 minutes |
| Taxotere/carboplatin/ Herceptin* | Docetaxel/carboplatin/trastuzumab every 3 weeks | 180 minutes post carbo |
| TC (Taxotere/Cytoxan) | Docetaxel/cyclophosphamide every 3 weeks | 180 minutes |
| TCHP (Taxotere/carboplatin/ Herceptin*/Perjeta*) | Docetaxel/carboplatin/trastuzumab/pertuzumab every 3 weeks | 180 minutes post carbo |
| THP (Taxotere/Herceptin*/Perjeta*) | Docetaxel/trastuzumab/pertuzumab every 3 weeks | 180 minutes post Taxotere |
The cap will go on for a “pre-cooling” period, which prepares your scalp for chemotherapy. It stays on after your infusion for a “post-cooling” period. Because chemotherapy drug levels peak in your system immediately after you complete an infusion, continued constriction of blood flow to your scalp for a few hours after treatment is the best way to protect your hair follicles. The length of the post-cooling period depends on the type of chemotherapy you’re getting and may include the time you’re receiving medications that don’t cause hair loss.
Common side effects include:
Low doses of an over-the-counter pain medication, such as Tylenol or Advil, can limit these symptoms. For best results, take it 30 minutes before the cold cap goes on your head. If you don’t bring pain medication to your appointment, feel free to ask the infusion nurse for it.
If bare skin is in direct contact with the cold cap, it can cause skin darkening and blisters. These gradually go away on their own. Protecting your bare skin can prevent this, and we will provide headbands or other shields for your skin, based on the device you use.
Different patients have different reasons for considering cold caps, such as:

Will it work for me?Everyone can expect to experience some degree of hair loss during chemotherapy. Outcome is dependent on several factors including chemotherapy regimen, dose, duration of drug infusion, chemotherapy drug metabolism and other medical considerations. It is not always possible to know how effective scalp cooling will be until you try it. Scalp cooling can minimize hair loss during chemotherapy, but you should be careful with your hair during treatment. Recommendations on how to take care of your hair while using DigniCap can be found by clicking the link below. Learn More |
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