Oral Chemotherapy options have advanced significantly over the past few years and it’s estimated the use will more than double in the next several years. One estimate puts 25 percent of anticancer agents in the research pipeline as “designated for oral administration”. The increased use of oral chemotherapy is moving the administration of cancer treatment from a medical facility to patient’s homes. While this is convenient to patients, it can lead to adherence and safety issues. Patients and caregivers are now responsible for ensuring the correct medication and dose at the correct time. This leads to the importance of education regarding safe handling of oral chemotherapy before and during treatment.